Dec 02, 2025  
2025-2026 Catalog 
    
2025-2026 Catalog
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CMLT 2133 - Clinical Microbiology II


Description
Clinical Microbiology II for Medical Laboratory Technician is an advanced course that builds upon the foundational knowledge from Clinical Microbiology I. This course delves deeper into the identification and characterization of pathogenic microorganisms, focusing on advanced diagnostic techniques and the clinical significance of various infections. Students will gain hands-on experience with molecular methods, antimicrobial susceptibility testing, and the latest developments in clinical microbiology.

Pre-Requisite
CMLT 2002 Orientation to Clinical Laboratory Science

CMLT 2013 Clinical Urinalysis & Body Fluids

CMLT 2114 Clinical Microbiology I

CMLT 2106 Clinical Practicum

Co-Requisite
N/A

Cross Listed Course
N/A

3 Credit Hour(s)

Contact Hours
45 Lecture, 15 Lab

4 Faculty Load Hour(s)

Semesters Offered
Spring

ACTS Equivalent
N/A

Grade Mode
A-F

Learning Outcomes
By the end of this course, students will be able to:

  • Apply advanced microbiological techniques for the identification of pathogens.
  • Perform and interpret molecular diagnostic tests.
  • Conduct antimicrobial susceptibility testing and understand resistance mechanisms.
  • Correlate microbiological findings with clinical presentations and outcomes.
  • Implement infection control practices and outbreak investigations.


General Education Outcomes Supported
  • Students develop higher order thinking skills


Standard Practices

Topics list

•  Advanced Bacterial Pathogens and Diseases:

Gram-positive and gram-negative bacteria: emerging pathogens

Anaerobic bacteria and their clinical significance

Mycobacteria and other acid-fast organisms

•  Fungal and Parasitic Infections:

Identification of clinically significant fungi: molds and yeasts

Advanced techniques for diagnosing parasitic infections

Fungal and parasitic infections in immunocompromised patients

•  Viral Infections and Virology:

Overview of clinically important viruses

Diagnostic methods for viral infections: culture, serology, and molecular techniques

Emerging and re-emerging viral diseases

•  Molecular Diagnostics in Microbiology:

Polymerase chain reaction (PCR) and real-time PCR

Nucleic acid sequencing and metagenomics

Applications of molecular diagnostics in infectious disease detection

•  Antimicrobial Susceptibility Testing:

Principles and methods: disk diffusion, broth microdilution, E-test

Interpretation of susceptibility results and clinical implications

Mechanisms of antimicrobial resistance and resistance patterns

•  Clinical Correlation and Case Studies:

Interpretation of complex laboratory results in a clinical context

Case studies involving multi-drug resistant organisms

Role of the clinical microbiologist in patient management and treatment decisions

•  Infection Control and Epidemiology:

Principles of infection control in healthcare settings

Outbreak investigation and management

Role of the laboratory in infection prevention and control

•  Quality Control and Quality Assurance in Microbiology:

Principles of quality control in advanced microbiological testing

Troubleshooting and corrective actions

Documentation, accreditation, and regulatory compliance

 

 

Learning activities

  • Lectures: In-person or online sessions covering advanced theoretical aspects.
  • Laboratory Practicals: Hands-on training in advanced microbiological techniques.
  • Case Studies: Real-world scenarios to illustrate clinical applications.
  • Guest Speakers: Insights from experienced clinical microbiologists and infectious disease specialists.
  • Assignments and Quizzes: Regular assessments to reinforce learning.

 

Assessments

  • The final exam is a course comprehensive exam. Results of the departmental finals will be submitted to the coordinator as part of course outcome assessment. The test will cover a select number of the core learning outcomes.

 

 

 



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